Rectal Acetaminophen Use During Oocyte Retrievals to Reduce Post-Operative Opioid Utilization

• Status: Terminated
• Trial end date: 2021-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The primary aim of this study is to evaluate the administration of rectal acetaminophen to current and standard anesthesia and analgesia protocol in oocyte retrievals would reduce postoperative utilization of opioids (Tylenol with codeine) in fertility patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of South Florida
• Treatments: Acetaminophen; Analgesics, Opioid; Fentanyl; Propofol

Criteria

Inclusion Criteria:

• Any female patient undergoing oocyte retrieval by transvaginal ultrasound-guided ovarian puncture

Exclusion Criteria:

• Patients with chronic pain conditions such as fibromyalgia and sickle cell anemia.

• Patient with BMI greater than 40

• Patients that required general endotracheal intubation anesthesia in prior oocyte retrieval

• Patients with documented allergic reaction to acetaminophen

• Patient with contra-indication to the use of acetaminophen (liver disease)

• Patients with a history of past or current alcohol, drug or opioid abuse

• Patients with ulcerative colitis, Crohn's disease, or severe rectal hemorrhoids