Red Blood Cell ATP Release and Vascular Function in Humans
Status:
Completed
Trial end date:
2018-10-05
Target enrollment:
Participant gender:
Summary
Previous work demonstrates that the red blood cells of older adults do not release a potent
vasodilator (ATP) as well as the red blood cells of younger adults. The investigators are
targeting a pathway within the red blood cell using fasudil hydrochloride to determine if
both the release of ATP from red blood cells and blood flow responses to low oxygen (hypoxia)
and exercise in older adults can be improved.