Overview

Reduced Doses of Antimony Plus Ranulocyte Monocyte Colony Stimulating Factor (GM-CSF) for Cutaneous Leishmaniasis

Status:
Completed
Trial end date:
2007-05-01
Target enrollment:
Participant gender:
Summary
The present study was designed as a randomized, single blind, placebo-controlled, study to evaluate the effect of 400 µg of recombinant human GM-CSF applied intralesionally and associated with half of the total dose of antimony in a reduced time schedule (20mgSbV/Kg/d for 10 days) as compared to the full dose of antimony (20mgSbV/Kg/d for 20 days) to treat cutaneous leishmaniasis ulcers.
Phase:
Phase 2
Details
Lead Sponsor:
Hospital Universitário Professor Edgard Santos
Collaborator:
Fundação de Amparo à Pesquisa do Estado da Bahia
Treatments:
Meglumine Antimoniate
Sargramostim