Overview

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Status:
Recruiting
Trial end date:
2024-06-01
Target enrollment:
Participant gender:
Summary
Reduced intensity conditioning (RIC) has been increasingly adopted as a modality to allow preparative conditioning pre-transplant to be tolerated by older adults or those patients that are otherwise unfit for myeloablative conditioning. In this study Reduced intensity conditioning (RIC) conditioning is used and followed by match aploidentical donor peripheral blood stem cell transplantation.
Phase:
Phase 1
Details
Lead Sponsor:
Stanford University
Collaborator:
Orca Biosystems, Inc.
Treatments:
Alkylating Agents
Cyclophosphamide
Fludarabine
Fludarabine phosphate
Lenograstim
Melphalan
Plerixafor
Sargramostim
Tacrolimus