Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
Status:
Recruiting
Trial end date:
2022-11-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to evaluate the efficacy of using a reduced-intensity
condition (RIC) regimen with umbilical cord blood transplant (UCBT), double cord UCBT,
matched unrelated donor (MUD) bone marrow transplant (BMT) or peripheral blood stem cell
transplant (PBSCT) in patients with non-malignant disorders that are amenable to treatment
with hematopoietic stem cell transplant (HSCT). After transplant, subjects will be followed
for late effects and for ongoing graft success.