Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)

• Status: Recruiting
• Trial end date: 2022-05-15
• Target enrollment: 0
• Participant gender: All

Summary

This is a study to determine if the incidence of infection at the Surgical SitE is impacted if with Antibiotic Irrigation is used during Ventral Hernia Repair (RINSE Trial)

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Greenville Health System; Prisma Health-Upstate
• Collaborators: New Hanover Regional Medical Center; Ohio State University; Oregon Health and Science University; Penn State University; The Cleveland Clinic; University of Pennsylvania; Washington University School of Medicine
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Clindamycin; Clindamycin palmitate; Clindamycin phosphate; Gemcitabine

Criteria

Inclusion Criteria:

• Age >18 y/o.

• Elective, open ventral hernia repair in a retromuscular fashion, with or without TAR.

• Clean, clean-contaminated, or contaminated wounds.

Exclusion Criteria:

• Age <18 y/o.

• Pregnancy.

• Emergency hernia repair.

• Laparoscopic, robotic, or hybrid approach.

• Dirty wounds.

• Use of biologic or absorbable synthetic mesh.

• Onlay, intraperitoneal or preperitoneal mesh placement.