Overview

Reducing the Abuse Liability of Prescription Opioids

Status:
Completed
Trial end date:
2020-01-01
Target enrollment:
Participant gender:
Summary
Opioid (commonly called narcotic) pain medicines are, after marijuana, the most commonly abused substances in the United States. Patients who take opioids for legitimate reasons may become addicted; for example, as many as 1 in 4 patients meet the criteria for current opioid dependence. It is very important that a way is found to provide pain relief while minimizing the addiction potential of these widely used pain medications. The study aim to find out if the use of another type of medication given in addition to an opioid will reduce the addiction potential of the opioid. The study is trying to find out if the ability of the opioid to relieve pain is changed when given with the other medication, and to see if the euphoric sensation or "liking" of the opioid pain medication is reduced when taken with the other medication.
Phase:
Early Phase 1
Details
Lead Sponsor:
The University of Texas Health Science Center at San Antonio
Treatments:
Oxycodone
Risperidone
Ziprasidone