Overview

Reduction of Plasma Free VEGF-A Using Low-dose Bevacizumab in Hemodialysis Patients

Status:
Withdrawn
Trial end date:
2021-11-01
Target enrollment:
Participant gender:
Summary
The primary purpose of this pilot study is to assess the pharmacokinetic profile of low-dose bevacizumab and its effectiveness in reducing plasma free VEGF-A levels safely in hemodialysis patients. This information will be used to plan a phase 1 clinical trial evaluating bevacizumab's role in hemodialysis vascular access failure.
Phase:
Early Phase 1
Details
Lead Sponsor:
Mayo Clinic
Treatments:
Bevacizumab
Endothelial Growth Factors