Reduction of Post-operative Endodontic Pain

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine the effect of intraligamentary injection of Lornoxicam on the intensity of post-operative endodontic pain in the tooth with symptomatic irreversible pulpitis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Islamic Azad University, Tehran
• Treatments: Lornoxicam; Piroxicam

Criteria

Inclusion Criteria:

• healthy (ASA I, II);

• Patients with first or second mandibular molars who need endodontic treatment;

• Vital tooth without a history of past endodontic treatment;

• Patients with clinical evidence of irreversible Pulpits with moderate to severe pain;

• Patients without pre apical lesion and periodontal ligament enlargement more than 0.75-1mm on the x-ray images;

• Patients in the age group of 18-65 years old

Exclusion Criteria:

• Pregnant or nursing;

• necrotic tooth;

• Patients with allergy or contraindication toward non-opioid or opioid painkillers such as aspirin or NSAIDs;

• People who have a history of acute peptic ulcer, during the past 12 months;

• People who have bleeding problems or have been taking anticoagulant drugs over the past month;

• Patients who have taken opioid or non opioid or steroid pain killers, antidepressants or sedative drugs.