Reduction of Rocuronium-induced Injection Pain With Aspiration of Blood

• Status: Not yet recruiting
• Trial end date: 2024-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to learn about reduction of rocuronium injection pain in participants receiving general anesthesia. The main question aims to answer is whether diluting rocuronium with blood can reduce rocuronium injection pain. Rocuronium is a rapid onset muscle relaxant used in general anesthesia. Lidocaine is a local anesthetic. Researchers will

• inject diluted rocuronium in participant's intravenous catheter during induction. • record withdrawal movement and rocuronium onset time and duration measured by train-of-four (TOF).

Researchers will compare between rocuronium diluted with blood, lidocaine and normal saline to see if blood can reduce rocuronium injection pain.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Chang Gung Memorial Hospital
• Treatments: Lidocaine; Rocuronium

Criteria

Inclusion Criteria:

• Willing to sign the written informed consent form.

• Males and females aged 18 to 65.

• Undergoing endotracheal intubation under general anesthesia.

• Anesthesia physical status classification II or below.

Exclusion Criteria:

• estimated glomerular filtration rate less than 60

• History of cirrhosis or liver failure

• Neuromuscular disease or neurological symptoms

• Mental illness

• Arrhythmia