Reduction of Tacrolimus Dose in Association With Mycophenolate Mofetil After Liver Transplantation
Status:
Terminated
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
The prevention of graft rejection after liver transplantation benefits nowadays from a
variety of newly developed immunosuppressive agents. This allows more flexible and
individualized immunoprophylaxis and gives an opportunity to reduce the long-term side
effects (hypertension, renal failure, diabetes, etc.) of immunosuppression. The purpose of
this study is to evaluate, in liver transplanted patients, if low doses of tacrolimus, given
in combination with mycophenolate mofetil, can result in a lower rate of long-term side
effects without increasing the rate of graft rejection.