Regional Anesthesia to Reduce Opioid Use Following FESS

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Opioids are prescribed for moderate to severe pain disorders; however, there are contraindications and side effects that are common to all opioids. The investigators hypothesize using regional anesthetic during sinus surgery will reduce surgical pain, therefore decreasing the need for post-operative opioid medication. The primary of objective is to determine if a long-acting local regional anesthetic applied during a surgery will reduce post-operative oral opioid usage.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Alabama at Birmingham
• Treatments: BB 1101; Bupivacaine; Dexamethasone; Dexamethasone acetate

Criteria

Inclusion Criteria:

• Age 18 years or older

• Able to sign informed consent form

• Able to comply with all study procedures and availability for the duration of the study

• Able to speak English

• Diagnosis of chronic rhinosinusitis

• Scheduled to receive functional endoscopic sinus surgery (FESS) at UAB

Exclusion Criteria:

• Current use of opioid medication

• Known allergic reactions to components of the study intervention

• History of IV drug use or abuse

• History of opioid abuse

• History of chronic pain disorder

• Treatment with another investigational drug or other intervention within 30 days