Within large number of patients with obesity, it is crucial to determine who is at the
greatest risk for development of chronic heart disease. The investigators previous studies
suggest that an excessive accumulation of fat in heart cells precedes the development of
obesity-related pathologies and may serve as a biomarker of heart disease in high-risk
population. Until now, the evaluation of fat in the human heart was possible postmortem or by
biopsy. The investigators novel magnetic resonance spectroscopy technique enables the
quantification of intracellular lipid content non-invasively and repeatedly in humans in
vivo. It could be used to better screen and treat obese patients at risk for the development
of metabolic disease. The investigators hypothesize that in obese humans with elevated
myocardial triglycerides, treatment with Nebivolol will reduce myocardial fat and will
improve heart function.