Relationship Between Topiramate Use and Ocular Angle Status

• Status: Unknown status
• Trial end date: 2007-07-01
• Target enrollment: 0
• Participant gender: All

Summary

We test the hypothesis whether topiramate narrows the angles which may render Asians more likely to suffer from acute angle closure glaucoma.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chinese University of Hong Kong
• Collaborator: Hong Kong Eye Hospital
• Treatments: Topiramate

Criteria

Inclusion Criteria:

• Participants aged 18-75 with an indication for starting topiramate.

Exclusion Criteria:

• Patients with known allergy or intolerance to topiramate.

• Recent exposure to topiramate (<3 months).

• Moderate to severe renal failure.

• Known history of renal calculi or hepatic failure

• Inability to give informed consent.

• Pregnant women or women of child-bearing age who do not practise an acceptable means of contraception.

• Patients known to have angle-closure glaucoma.