Relative Bioavailability of Different Formulations of BI 671800 in Healthy Male and Female Volunteers
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
To compare the oral bioavailability and rate of absorption of two different formulations of
BI 671800 HEA (choline salt) tablets 200 mg, one with enteric coating (EC) and one without
EC, versus 2 x 100 mg BI 671800 ED (ethylenediamine salt) capsules. Both BI 671800 HEA
formulations were further investigated concerning food effect and one of the two BI 671800
HEA formulations identified by interim pharmacokinetic analysis was further investigated
concerning dose proportionality with 50 mg.