Relative Bioavailability of Ferric Pyrophosphate From an Apple Juice Drink

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to find out how well iron is absorbed when a newly developed form of ferric pyrophosphate is added to a commercial apple juice drink.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Institute of Food Research; Quadram Institute Bioscience
• Collaborator: The Coca-Cola Company
• Treatments: Iron

Criteria

Inclusion Criteria:

• Women

• Age >18 and <65

• BMI >18.5 and <35

• Serum ferritin value of =12μg/L and =50μg/L

Exclusion Criteria:

• Men

• Age < 18 or >65

• BMI <18.5 or >35

• Serum ferritin value of <12μg/L or >50μg/L

• Volunteers will be excluded if they are found to have depressed or elevated blood pressure measurements (<90/50 or<95/50 if symptomatic or >160/100)

• Diagnosed with a long-term illness requiring active treatment, e.g. diabetes, cancer, cardiovascular disease

• Gastrointestinal disease (excluding hiatus hernia unless symptomatic)

• Regular prescribed medication that may interfere with iron metabolism

• Regular use of antacids and laxatives (at least once a week)

• Women who are pregnant or less than 12 months since giving birth

• Women breast feeding

• Vitamin supplements with or without minerals if taken more than once a week, and unwillingness to discontinue occasional use for the duration of study

• Unwillingness to discontinue use of herbal supplements for the duration of study

• Use of antibiotics within four weeks prior to study start

• Parallel participation in another study which involves dietary interventions or sampling of blood that may increase the volume taken above 500ml in a 4-month period.

• Asthma requiring treatment within the last two years

• Results of clinical screening which indicate, or are judged by the HNU Medical advisor to be indicative of a health problem which could compromise the well-being of the volunteer if they participated or which would affect the study data.