Relative Bioavailability of Two Tepotinib Film-Coated Tablet Formulations in Healthy Volunteers
Status:
Completed
Trial end date:
2016-03-31
Target enrollment:
Participant gender:
Summary
This is a Phase I, open label, randomized, crossover trial to investigate the relative
bioavailability of tepotinib in healthy volunteers. Twenty-four volunteers will be randomized
to one of the two treatment sequences: Sequence A: test, reference, Sequence B: reference,
test. The reference treatment refers to the current Phase II film-coated tablet (5 * 100
milligram (mg) tepotinib film-coated tablets) and the test treatment to the new Phase III
film-coated tablet (1 * 500 mg film-coated tepotinib tablet).