Reloading Prasugrel or Clopidogrel on High Platelet Reactivity Before Percutaneous Coronary Intervention
Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
High platelet reactivity unit (PRU) after loading dose clopidogrel in patients undergoing
percutaneous coronary intervention (PCI) is related to high risk of short and long term
recurrent ischemic events including stent thrombosis.
The investigators hypothesize that additional loading of prasugrel in patients with high PRU
after clopidogrel loading would be superior to additional loading of clopidogrel in reducing
platelet reactivity and thereby result in lower risk of short term recurrent ischemic events.