Remifentanil Versus Dexmedetomidine for Post-Cardiac Surgery Patients With Noninvasive Ventilation Intolerance

• Status: Completed
• Trial end date: 2019-03-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare the sedation effects between remifentanil and dexmedetomidine in post-cardiac surgical patients who developed noninvasive ventilation (NIV) intolerance.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai Zhongshan Hospital
• Treatments: Dexmedetomidine; Remifentanil

Criteria

Inclusion Criteria:

• adult patients

• after cardiac surgery

• receiving noninvasive ventilation

• moderate to severe NIV intolerance (NIV intolerance score of 3 or 4)

Exclusion Criteria:

• difficult expectoration

• pregnancy or breastfeeding

• intensive care delirium screening checklist score more than 4

• drug abuse history

• known allergy to opiods

• cardiogenic shock

• malignant arrhythmias