Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous

• Status: Completed
• Trial end date: 2018-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

Remifentanil may be an ideal drug for labor analgesia due to its pharmacodynamic and pharmacokinetic profile. As compared to epidural analgesia, it demonstrated satisfactory for pain relief at the beginning of labour with a gradual elevation of pain scores as labour progresses. However, fast onset and limited time efficacy may render it useful in multiparous with a faster labor progression, thus even making it an alternative to single-shot spinal analgesia.

• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Medical Centre Ljubljana
• Treatments: Bupivacaine; Remifentanil

Criteria

Inclusion Criteria:

• patients' request for pain relief

• ASA physical status 1-3

• uncomplicated singleton pregnancy with cefalic presentation

• gestation age > 37 weeks

• regular uterine contractions

• cervical dilation 2-5 cm

• anticipated vaginal delivery

• fetus without suspected abnormality and normal CTG

Exclusion Criteria:

• contraindications for remifentanil usage

• contraindications for CSE