Remimazolam Bolus for General Anesthesia

• Status: Completed
• Trial end date: 2021-07-26
• Target enrollment: 0
• Participant gender: All

Summary

It is important to estimate the adequate dose of remimazolam intravenous bolus injection to induce the loss of consciousness. We will determine the ED50 and ED95 of remimazolam intravenous bolus on the loss of consciousness in patients undergoing general anesthesia.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Gangnam Severance Hospital

Criteria

Inclusion Criteria:

• Patients aged 19 years old or older, with American Society of Anesthesiologists Physical Status 1-3, and scheduled for general anesthesia

Exclusion Criteria:

1. Patients scheduled for liver surgery

2. Uncontrolled hypertension

3. Uncontrolled diabetes mellitus

4. Liver disease

5. Kidney disease

6. Intolerance or hypersensitivity to benzodiazepine

7. Addiction

8. Glaucoma

9. Heart failure

10. Peripheral vascular disease

11. Obstuctive lung disease

12. Patients scheduled for regional anesthesia before general anesthesia

13. Pregnancy