Remimazolam Versus Propopol Based Total Intravenous Anesthesia for Breast Surgery

• Status: Not yet recruiting
• Trial end date: 2022-08-31
• Target enrollment: 0
• Participant gender: All

Summary

Comparison of the incidence of hypotension under remimazolam and propofol-based anesthesia in patients undergoing breast surgery under general anesthesia

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Propofol

Criteria

Inclusion Criteria:

• Adult patients over the age of 19 undergoing elective breast cancer surgery under general anesthesia at Seoul National University Hospital

Exclusion Criteria:

• patients with acute narrow-angle glaucoma/ shock or coma/ acute alcohol poisoning/ sleep apnea/ alcohol or drug dependency/ severe or acute respiratory failure/ galactose intolerance/ Lapp lactase deficiency/ glucose galactose malabsorption/ severe hypersensitivity to dextran.

• Patients with myasthenia gravis/ pulmonary heart disease/ chronic obstructive pulmonary disease/ bronchial asthma

• Patients with cardiovascular diseases such as ischemic heart disease/ coronary artery disease/ angina pectoris/ myocardial infarction/ atherosclerosis/ arrhythmia/ cerebrovascular disease/ and stroke

• Patients with chronic renal failure

• Patients with severe hepatic impairment (Child Pugh class C)

• Patients with American Society of Anesthesiology score III or higher

• Patients with hypersensitivity to propofol and soy or peanuts

• Epilepsy patients

• Patient with fat metabolism abnormality

• Patients with high intracranial pressure

• Pregnant woman

• Patients unable to use supraglottic airway due to poor dental condition

• In cases that the researcher judges to be unsuitable for this clinical trial