Renal Function During Pediatric Anesthesia

• Status: Completed
• Trial end date: 2019-04-01
• Target enrollment: 0
• Participant gender: Male

Summary

It is known that volatile anesthesia, such as sevoflurane, retain water and that this appears more pronounced in children. However, the mechanisms for this effect is unknown and it is not clear if the commonly used anesthetic propofol does the same. In this study the investigators want to compare the fluid and electrolyte conserving effects of sevoflurane and propofol in a pediatric setting and also investigate humoral changes induced by these anesthetics.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Uppsala University
• Treatments: Anesthetics; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• Eligible for hypospadia surgery.

Exclusion Criteria:

• American Association of Anesthesiology class above 2

• Weight above 50 kg or below 10 kg

• Hypersensitivity towards the anesthetic agents (difficult peanut or soy allergy)

• Inability for parent to understand study information