Overview

Renoprotective Effect of Nisoldipine and Lisinopril in Type 1 Diabetic Nephropathy

Status:
Completed
Trial end date:
1999-04-01
Target enrollment:
Participant gender:
Summary
The aim of the study was to compare the renoprotective effect of a long acting calcium antagonist (nisoldipine) with an angiotensin converting enzyme inhibitor (lisinopril)in type 1 diabetic patients with diabetic kidney disease. In total, 51 patients were randomised to treatment with one of these drugs for 4 years. Changes in kidney function, blood pressure and urinary excretion of albumin were measured every 6 months
Phase:
Phase 4
Details
Lead Sponsor:
Steno Diabetes Center
Steno Diabetes Center Copenhagen
Collaborator:
Bayer
Treatments:
Lisinopril
Nisoldipine