Repeatability in Hyperpolarized 3-Helium With MRI

• Status: Completed
• Trial end date: 2012-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The main purpose of this study is to assess and test the reproducibility and results of hyperpolarized 3-Helium gas as a contrast agent with Magnetic Resonance Imaging (MRI) of the lungs in healthy adult subjects.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Eric A. Hoffman; University of Iowa
• Collaborator: National Institutes of Health (NIH)

Criteria

Inclusion Criteria:

• must be between the ages of 18 and 90

• must have a Body Mass Index (BMI) of < 32 and weigh < 200 lbs.

Exclusion Criteria:

• if female, must not be pregnant or breastfeeding

• must not have any metal objects in or on their body including body piercings that cannot be easily removed, bullets, metallic fragments or slivers in eyes, skin, etc., pacemaker or defibrillation, aneurysm clips, cochlear implants, coronary stents, or neurostimulation.

• must not have a history of claustrophobia, panic disorders, anxiety attacks, atrial fibrillation, uncontrolled high blood pressure, frequent ventricular ectopic rhythm, hemodynamic instability, kidney dysfunction or heart disease.