Overview

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Status:
Terminated
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
This protocol is a phase I/II, study of ascorbic acid (AA) infusions combined with treatment with irinotecan versus treatment with irinotecan alone in patients with recurrent or advanced colorectal cancer who have failed at least one treatment regimen with a 5-FU based therapy. This study will be conducted as an amendment to Investigational New Drug # 77486.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Thomas Jefferson University
Treatments:
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Ascorbic Acid
Camptothecin
Irinotecan
Molecular Mechanisms of Pharmacological Action
Vitamins