Research on Nicorandil Treatment of Patients Diagnosed as CHD (Coronary Heart Disease) With Stable Angina
Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
This study of 402 cases of stable angina subjects who were diagnosed as Coronary Heart
Disease (CHD) is a randomized, blank controlled, multi-center clinical study. Subjects who
are taking standard treatment with stable symptoms will receive a 24-hour ambulatory
electrocardiogram (ECG) (Holter) examination. They will be randomly divided into two groups.
The nicorandil group will receive nicorandil 5 milligram (mg) (3 times a day = tid) on top of
the standard treatment for 12 weeks, while the control group will stay on standard treatment.
Nitrates and beta blockers need to be maintained on a stable dose. Other drugs that do not
affect the primary endpoint may be adjusted per investigators decision.