Resistance Training and Testosterone After Spinal Cord Injury
Status:
Completed
Trial end date:
2017-12-30
Target enrollment:
Participant gender:
Summary
The goal of this proposal is to investigate the efficacy of a complimentary approach of
evoked resistance training and testosterone replacement therapy on the changes in body
composition and metabolic profile after SCI. The proposed method could become a recommended
and simple intervention especially for individuals with limited access and poor tolerance to
exercise. The rationale is based on the evidence that individuals with SCI experience decline
in anabolic hormones which may be responsible for the deterioration in body composition and
metabolic profiles and leads to increase obesity, type 2 diabetes mellitus, dyslipidemia and
subsequently cardiovascular disease. The designed study will provide explanation to the
adaptations in the energy source of the muscle cells in response to training.