Resolution of Pain and Swelling After the Use of Neem Leaf Extract Compared to Chlorhexidine Gluconate as an Intracanal Irrigant During Pulpectomy

• Status: Completed
• Trial end date: 2018-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The trial is to test the resolution of pain, swelling and other signs of periapical infection and the antimicrobial efficacy when using the neem leaf extract compared to chlorhexidine as root canal irrigant in Pulpectomy treatment for children.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Chlorhexidine; Chlorhexidine gluconate; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Patient and parent cooperation.

• Absence of any systemic disease that would contraindicate pulp therapy.

• Non vital molar teeth presenting with an acute or chronic periapical infection as a result of pulp necrosis ( Periapical abscess ,a sinus tract formation as a sequelae )

• Making sure the patient is not taking an antibiotic and has not taken it for the past 2 weeks.

• Absence of physiologic or pathologic root resorption that contraindicate pulp therapy.

• Restorable teeth

• Molars with at least two thirds of root remaining.

Exclusion Criteria:

• Children with any condition that contraindicates pulp therapy will be excluded (rheumatic fever, infective endocarditis , leukemia , corticosteroid therapy and immunosuppressed children).