Overview

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

Status:
Not yet recruiting
Trial end date:
2026-02-01
Target enrollment:
Participant gender:
Summary
This is a phase 1b prospective, single arm, open-label trial determining the efficacy and feasibility of using a ctDNA assay (test) result to help guide neoadjuvant chemotherapy in subjects with Stage IB, II or Stage III adenocarcinoma of the stomach or gastroesophageal junction (GEA).
Phase:
Phase 1
Details
Lead Sponsor:
University of California, Irvine
Collaborator:
Natera, Inc.
Treatments:
Carboplatin
Docetaxel
Folfirinox
Irinotecan
Nivolumab
Paclitaxel
Pembrolizumab