Response of Topical Capsaicin in Alopecia Areata

• Status: Completed
• Trial end date: 2000-06-01
• Target enrollment: 0
• Participant gender: All

Summary

It has been postulated that Alopecia Areata (AA) is, at least in part, a neurologically mediated disease. Research supporting this theory includes the finding that nerves surrounding the hair follicles are collapsed. We want to take this research a step further and show that not only are these perifollicular nerves collapsed, but that their function is also impaired.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Minnesota; University of Minnesota - Clinical and Translational Science Institute
• Treatments: Capsaicin

Criteria

Inclusion Criteria:

• Must have alopecia totalis or universalis.

• Be in good health.

• Not be taking any medications including topical medications

• Be 18 years or older.

• Be willing to apply study medication or vehicle as directed, comply with instructions and commit to follow-up visits.

• Not have had hair chemically treated (including colored hair, permed hair, etc) within the month prior to the study.

Exclusion Criteria:

• Absence of extensive alopecia areata.

• People not in good health.

• People taking medications.

• Allergies to capsaicin.

• Presence of irritated or visibly inflamed scalp.

• Having had hair chemically treated (including colored hair, permed hair, etc.) within the month prior to study.