Retrograde Intrarenal Stone Surgery - A Method of Treating the ESWL Resistant Kidney Stone

• Status: Unknown status
• Trial end date: 2007-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Is it possible to decrease the intrarenal pressure in the kidney during endoscopic management of kidney stone by topical administration of drugs? In order to secure fewer complications in ureteroscopic operations the pharmacological agent isoproterenol is tested on pigs and human to determine its potential of lowering intrarenal pressure.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fredericia Hosptial
• Treatments: Isoproterenol

Criteria

Inclusion Criteria:

• Indication for RIRS procedure

• Age > 18 years

• Normotensive

• Capable of understanding information given

Exclusion Criteria:

• Previous myocardiac infarct

• Daily use of alpha- og beta- blocking medicine og calcium antagonists

• Use of NSAID the last 2 days

• Stone in the ureter

• Declared

• Known malignant disease in urinary tract

• Bladder disease

• Nephrostomies inserted

• JJ-catheters inserted

• Prisoners

• Pregnant

• Nursing mothers