Reversal of Ketamine Pharmacodynamic Effects With Naloxone

• Status: Terminated
• Trial end date: 2017-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether the analgetic and other effects effect of ketamine are partly mediated through opioid receptors

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ullevaal University Hospital
• Collaborator: University of Oslo
• Treatments: Ketamine; Naloxone

Criteria

Inclusion Criteria:

• Females of norwegian Caucasian origin who needs surgical removal of impacted third molars

Exclusion Criteria:

• Anamnestic information regarding psychiatric diagnosis regarding mother/father or brother/sister Concommitant medication other than oral contraceptives Hypersensitivity towards NSAID/opioids/study drugs Females with suspected or confirmed pregnancy Lactating females Surgery lasting more than 60 minutes