Reversal of an Unfavorable Effect of Hydrochlorothiazide Compared to Angiotensin Converting Enzyme Inhibitor on Serum Uric Acid and Oxypurines Levels by Estrogen-progestin Therapy in Hypertensive Postmenopausal Women.

• Status: Completed
• Trial end date: 2005-11-17

Summary

The aim was to assess the effect of estrogen-progestin therapy (EPT) on serum levels of uric acid (SUA) and its precursors: xanthine (X) and hypoxanthine (HX) and on uric acid (UA) renal excretion in hypertensive postmenopausal women treated with an angiotensin-converting enzyme inhibitor (ACEI) or thiazide diuretic (HCTZ).

• Phase: Phase 4

Details

• Lead Sponsor: Anna Posadzy-Małaczyńska
• Treatments: Angiotensin-Converting Enzyme Inhibitors; Enzyme Inhibitors; Estradiol; Estradiol 17 beta-cypionate; Estradiol 3-benzoate; Estrogens; Hydrochlorothiazide; Norethindrone; Norethindrone Acetate; Perindopril; Polyestradiol phosphate; Progestins; Uric Acid