Riociguat Versus Balloon Pulmonary Angioplasty in Non-operable Chronic thromboEmbolic Pulmonary Hypertension
Status:
Completed
Trial end date:
2020-01-27
Target enrollment:
Participant gender:
Summary
"Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe form of pulmonary
hypertension characterized by obstruction of the pulmonary vasculature by residual organized
thrombi, leading to increased pulmonary vascular resistance (PVR), progressive pulmonary
hypertension, and right failure.
In patients deemed operable, pulmonary endarterectomy (PEA) is the gold standard treatment
and is the only potentially curative treatment. However, some patients are ineligible for
surgery owing to occlusion of distal vessels. The best treatment option for these
non-operable CTEPH patients is not yet established.