Risk and Prevention Study: Evaluation of the Efficacy of n-3 PUFA in Subjects at High Cardiovascular Risk
Status:
Completed
Trial end date:
2011-10-01
Target enrollment:
Participant gender:
Summary
In the everyday practice cardiovascular prevention in people at high risk is still
unsatisfactory and treatments with documented efficacy are generally under-used.
Polyunsaturated fatty acids of marine origin (n-3 PUFA) are the latest more promising
strategy to improve prognosis in these patients.
The Risk and Prevention study combines an epidemiological and an experimental approach in
order to:
1. Verify the possibility to optimise cardiovascular prevention in subjects at high risk by
planning the intervention with patients and setting individual goals (outcome study)
2. Evaluate the efficacy of a long term n-3 PUFA treatment in reducing the incidence of
cardiovascular events, through a controlled, randomised, double blind clinical trial.
Phase:
Phase 3
Details
Lead Sponsor:
Mario Negri Institute for Pharmacological Research