Overview

Risk of Developing Antibodies to Heparin-PF4 After Heart Surgery

Status:
Completed
Trial end date:
2012-07-01
Target enrollment:
Participant gender:
Summary
Heparin is a drug that is widely used to prevent and treat blood clotting. Individuals undergoing cardiopulmonary bypass surgery are administered high doses of heparin, and some of them develop antibodies to the drug. This immune response can lead to the formation of blood clots, setting the stage for a potential heart attack or stroke. The purpose of this study is to evaluate how often an immune response to heparin leads to the formation of blood clots in individuals who have had heart surgery.
Details
Lead Sponsor:
Duke University
Treatments:
Antibodies
Calcium heparin
Heparin