Risk of Methicillin-resistant S.Aureus (MRSA) Infections in MRSA Carrier Under Introduction of Rapid MRSA Screening
Status:
Completed
Trial end date:
2012-02-01
Target enrollment:
Participant gender:
Summary
This study was designed to evaluate the effect of a targeted preoperative
Methicillin-resistant Staphylococcus aureus (MRSA) detection by polymerase chain reaction
(PCR) on either endogenous or exogenous postoperative MRSA infections in a high risk
population undergoing gastroenterological surgery. The primary endpoint was to investigate
whether the potentially high incidence of MRSA infections in patients with MRSA nasal
colonization before surgery can be prevented with a PCR-based strategy. The second endpoint
was to investigate the impact of acquisition of MRSA colonization after surgery on the
occurrence of MRSA infections. Investigators hypothesize that postoperative MRSA infection is
prevented by a targeted screening strategy in preoperative MRSA carrier, and there is limited
effect in patients with postoperative MRSA acquisition.