Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade

• Status: Completed
• Trial end date: 2015-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this protocol is to learn more about impulsive decision making in people who use methamphetamines. The investigators would like to know if a medication called naltrexone changes how people make decisions. The investigators would also like to know whether changes in decision making can be observed by MRI (magnetic resonance imaging).

The research is conducted in Portland, OR.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oregon Health and Science University
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Methamphetamine; Naltrexone

Criteria

Summary Inclusion Criteria:

• Diagnostic and Statistical Manual (DSM)-IV Methamphetamine Dependence

• Deemed healthy enough to participate by study physician

• Age 18-55

• Right handed

• English-speaking

Summary Exclusion Criteria:

• Current opioid use in the last 30 days; opioid abuse or dependence within past 5 years

• Pregnancy

• MRI contraindications (e.g. metal in head).

The research is conducted in Portland, OR.