Risperidone (Risperdal) Augmentation in Depressed Partial Responders to SRI Treatment
Status:
Withdrawn
Trial end date:
2006-03-01
Target enrollment:
Participant gender:
Summary
This is a study of the chemistry of depression in people who are taking an antidepressant but
it is not working well. The changes in brain chemicals that occur when an SSRI type
antidepressant is supplemented with risperidone (Risperdal®) will be studied. Spinal fluid is
used to measure chemical levels of dopamine, serotonin, and other chemicals thought to be
involved in depression. The study has potential to help understand and treat depression.