Rivastigmine Patch Effect on the Post-operative Delirium in Patients at Risk of Dementia.

• Status: Completed
• Trial end date: 2015-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Delirium is a common and serious condition and is associated with adverse outcome. The elderly who have cognitive dysfunction are expected to show delirium more frequently. It is most likely that delirium represents a response to impaired cholinergic neurotransmission. Investigators aimed to establish the preventive effect of the cholinesterase inhibitor, rivastigmine patch, on the post-operative delirium limited to femur neck fracture operation in patients at risk of dementia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chung-Ang University Hosptial, Chung-Ang University College of Medicine
• Treatments: Rivastigmine

Criteria

Inclusion Criteria:

• Consecutively enrolled the patients who is going to operation after femur neck fracture.

• Patients agree to the informed consent.

Exclusion Criteria:

• depressive mood and their geriatric depression scale is over 6 / 15.

• Their Korean version MMSE(minimental status examination) are over 25, or global dementia scale (GDS) are under 3 or over 5.

• any delirious state at pre-operation period by DSM IV and CAM (Confusion Assessment Method)