Role Of Pregabalin To Decrease Postoperative Pain In Microdiscectomy

• Status: Completed
• Trial end date: 2020-04-17
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the effect of pregabalin in reducing the neuropathic pain in postoperative patients who have undergone single level Microdiscectomy for prolapsed intervetebral lumbar disc.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ziauddin University
• Treatments: Pregabalin

Criteria

Inclusion Criteria:

• All patients with severe CLBP and/or leg pain

• Patients with static or dynamic leg pain

• Patients with leg pain resulting from localized lumbar or lumbosacral segmental instability

• Spinal stenosis at levels L2-S1 or caused by isthmic spondylolisthesis (grade I and II)

Exclusion Criteria:

• Patients with previous lumbar surgery

• Patients allergic to gabapentinoids

• Patients with renal impairments

• Patients who are already on opioids, benzodiazepines, barbiturates, ethanol (alcohol)

• Patient presented with diabetes and other drugs that depress the central nervous system

• Patients who are already on ACE inhibitors as they may enhance the adverse/toxic effect of Pregabalin.