Role of Alphacalcidol Supplement to Reduce Pain and COMP in Geriatric Knee Osteoarthritis Patients
Status:
Completed
Trial end date:
2017-12-31
Target enrollment:
Participant gender:
Summary
Indonesian population's life expectancy has been increasing steadily in the last 3 decades.
It potentially increases the prevalence of degenerative diseases, including osteoarthritis
(OA). Serum Vitamin D (25(OH)D) level has been recognized as a risk factors for knee OA.
Cartilage Oligomeric Matrix Protein (COMP) is cartilage degradation product can be used as a
diagnostic marker for knee OA. This study aims to determine the effect of Vitamin D
supplementation (Alphacalcidol) on pain based on WOMAC indicators and joint cartilage
condition based on COMP serum markers in knee OA elderly patients.
Phase:
Phase 3
Details
Lead Sponsor:
Syarif Hidayatullah State Islamic University Jakarta