Overview Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone Status: Unknown status Trial end date: 2011-01-01 Target enrollment: Participant gender: Summary The purpose of this study is to determine to what extent CYP2B6, CYP3A4, and MDR1 polymorphisms affect the metabolism of methadone. Phase: Phase 1 Details Lead Sponsor: University of WashingtonTreatments: BupropionDigoxinMethadoneMidazolam