Overview

Role of Folinic Acid in Improving the Adaptive Skills and Language Impairment in Children With Autism Spectrum Disorder

Status:
Completed
Trial end date:
2021-03-30
Target enrollment:
0
Participant gender:
All
Summary
No such study has been conducted in Pakistan so the primary objective of this study was to determine the role of folinic acid in improving the speech and adaptive skills while secondary objective was improvement of stereotype movements and hyperactivity in ASD among children aged 3 to 14 years.
Phase:
Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Nishtar Medical University
Treatments:
Folic Acid
Leucovorin
Levoleucovorin
Criteria
Inclusion Criteria:

- Children of both genders aged 3 to 14 years with diagnosis of autism spectrum disorder
established by DSM-5 Criteria, Childhood Autism Rating Scale (CARS) scoring and
clinical examination along with documentation of Language Impairment

Exclusion Criteria:

- All children having autism with seizure disorder, autism with serious medical illness
within last 6 months or those with autism with well-defined genetic syndrome.