Role of Hydroxychloroquine to Improve Endothelial Dysfunction in Patients With Rheumatoid Arthritis
Status:
Completed
Trial end date:
2017-09-30
Target enrollment:
Participant gender:
Summary
Rheumatoid arthritis (RA) increase cardiovascular risk and endothelial dysfunction.
Hydroxychloroquine (HCQ) is expected to improve endothelial dysfunction through some
metabolic effects. The investigators intend to find the role of HCQ to improve endothelial
dysfunction in RA patients. This study will also evaluate correlation HOMA-IR (homeostasis
model assessment-estimated insulin resistance), FFA (free fatty acid) and ox-LDL
(oxidized-LDL) level change, with endothelial dysfunction improvement.