Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis
Status:
Active, not recruiting
Trial end date:
2025-12-31
Target enrollment:
Participant gender:
Summary
Ulcerative colitis (UC) is a chronic inflammatory disorder of the gastrointestinal tract of
unknown etiology. UC is characterized by recurring episodes of inflammation limited to
mucosal and submucosal layers of the colon. The object of the present study was to determine
the prevalence of intestinal protozoa and helminthes in UC patients, and the role of this
changes in aetiopathogenesis of diseases. Patients will be examined before and after therapy.
Parasites and protozoa prevalence and intensity will be detected by triple
coproscopy.Microbiological study will be conducted before therapy for detection pathogenic
bacteria only from UC patients infected with B. hominis . If intestinal pathogenic bacteria
are found, participants will be excluded from further investigation.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan