Role of Intravenous Lipid Emulsion in Improving Coma of Acute Antipsychotics Poisoning

• Status: Recruiting
• Trial end date: 2021-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Intravenous Lipid Emulsion in Improving Coma Of Antipsychotic drugs Acute Poisoning: A Randomized Controlled Trial in Poison Control Center of Ain Shams University Hospitals

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Fat Emulsions, Intravenous; Soybean oil, phospholipid emulsion

Criteria

Inclusion Criteria:

• All adult comatose patients admitted to the ICU of Poison Control Center of Ain Shams University Hospitals with positive history of antisychotic drugs overdose during the period starting from the beginning of March 2020 to the end of Septemper 2021

Exclusion Criteria:

• Based on the possibility of heterogeneity in hemodynamic parameters, laboratory variables, GCS and/or AVPU Scale, the following patients will be excluded:

• Patients less than 18 years and more than 65 years.

• Pregnant and lactating females.

• Co-ingestion of other agents.

• Presence of medical diseases (e.g. renal, hepatic, cardiovascular diseases) and chronic pancreatitis.

• History of head trauma.

• Presence of conditions where ILE is contraindicated.