Role of Metformin on Muscle Health of Older Adults
Status:
Recruiting
Trial end date:
2022-04-30
Target enrollment:
Participant gender:
Summary
Muscle atrophy and insulin resistance are common after bed rest in healthy older adults.
Metformin treatment has been shown to improve insulin sensitivity and attenuate muscle loss
in insulin resistance adults though the mechanisms are not fully known. Metformin used as a
preventive strategy to maintain muscle and metabolic health in bed ridden older adults has
not been investigated.