Role of Oral Chlorhexidine Gel in Prevention of Ventilator Associated Pneumonia

• Status: Completed
• Trial end date: 2009-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if oral mucosal application of chlorhexidine gel will prevent the development of ventilator associated pneumonia in children.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: All India Institute of Medical Sciences, New Delhi
• Treatments: Chlorhexidine; Chlorhexidine gluconate

Criteria

Inclusion criteria:

1. Patients in PICU requiring mechanical ventilation

2. Above the age of 3 months

3. Oro or nasotracheal intubation

Exclusion criteria:

1. Known hypersensitivity to chlorhexidine

2. Inability to access the oral cavity for any reason

3. Patients with tracheostomy

4. Mechanical ventilation for more than 24 hours prior to PICU admission.

5. Death or extubation within 24 hours of ICU admission.